Journal of Applied and Natural Science 8 (1): .506-514 (2016)
Antimicrobial photodynamic therapy and its applicability in aquaculture systems and aquatic animal health management: An overview
Pooja Kanyal1, Rameez Roshan P.M.2, Mohd Danish3, Anita4, Akansha khati5 and
1Department of Aquatic Animal Health Management, Central Institute of Fisheries Education, Mumbai- 400 060, INDIA.
2Department of Fish Genetics and Breeding, Central Institute of Fisheries Education, Mumbai- 400 060, INDIA.
3Department of Fisheries Resource Management, College of Fisheries, G. B. Pant University of Agriculture &
Technology, Pantnagar-263145 (Uttarakhand), INDIA
4,5,6Department of Aquaculture, College of Fisheries, G. B. Pant University of Agriculture & Technology, Pantnagar-
263145 (Uttarakhand), INDIA
*Corresponding author. E-mail: firstname.lastname@example.org
Abstract : Global aquaculture production in 2012 touched new high of 90.4 million tonnes including 66.6
million tonnes of food fish and 23.8 million tonnes of aquatic algae providing 19.2 kg per capita food fish
suppy. Aquaculture is reported to suffer heavy production and financial losses due to fish infections
caused by microbial pathogens. Therefore in order to make aquaculture industry more sustainable, effective strategies to control fish infections are urgently needed. Antimicrobial Photodynamic Therapy
(aPDT) is an emerging, low-cost anti-microbial approach to the treatment of locally occurring infections
and also for the treatment of aquaculture water and waste waters. Already proven effective in various
medical and clinical applications, it utilizes three vital components: a photosensitizing agent (PS), a light
source of an appropriate wave length and oxygen. aPDT has got a potential of being a preferred choice
over antibiotics in aquaculture systems because of its non-target specificity, few side effects, lack of the
pathogenicity reversal and re-growth of the micro-organism after treatment and the lack of development
of resistance mechanisms. The technique has been proved effective in vitro against bacteria (including
drug-resistant strains), yeasts, fungi, viruses, parasites and even the stubborn biofilms. Although preliminary
results indicate that this technology has a high potential to disinfect waters in aquaculture system and also in hatcheries and seed production units, but it clearly needs more deep knowledge and multi-dimenstional approach.
Keywords : Antibiotic resistance, Antimicrobial photodynamic therapy, Fish farming, Photosensitizer