Applied and Natural Science Foundation
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Journal of Applied and Natural Science
An International Journal | Print ISSN: 0974-9411 | Online ISSN: 2231-5209
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Abstract
Journal of Applied and Natural Science 6 (1): 12-13 (2014)
A study on few biochemical parameters of clinically suspected and laboratory confirmed Leptospirosis cases
D. B. Zala¹, Vikram Khan², and V. K. Das*
*Department of Medicine, Sri Vinoba Bhave Civil Hospital, Dadra & Nagar Haveli, Silvassa -396230, INDIA
¹Department of Microbiology, DPHL, VBCH, Directorate of Medical & Health Services, Dadra & Nagar Haveli,Silvassa - 396230, INDIA
²Directorate of Medical & Health Services, Dadra & Nagar Haveli, Silvassa, 396230, INDIA
*Corresponding author. E-mail:vkdas511@gmail.com
Abstract : A study on biochemical parameters in clinically suspected and laboratory- confirmed leptospirosis cases was conducted in the Union Territory of Dadra and Nagar Haveli. Out of 50 clinically suspected samples of leptospirosis, 38% were positive from both ELISA IgM and rapid card test. In the present study, liver markers such as bilirubin, Serum Glutamate Oxalo acetic Transaminase (SGOT) and Serum Glutamate Pyruvic Transaminase (SGPT) encountered elevation 68%, 100% and 89% respectively in leptospiosis positive patent while 89% and 48 % of positive patients showed elevation in kidney marker, creatinine and blood urea. On the basis of liver and renal functions, a hospital can develop its own clinical algorithm to suspect the case of leptospirosis.

Keywords : Biochemical parameters, Immunochromatogaphy, SGOT, SGPT, Leptospirosis
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