Journal of Applied and Natural Science 5 (2): 335-337 (2013)
Antibacterial activity of actinomycetes against bacterial pathogens of diabetic foot ulcers
M. Saraswathi2* and N. Mallikarjuna1
1Department of Microbiology, S.V.University, Tirupati-517 501, INDIA
2Department of Applied Microbiology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517 502, INDIA
*Corresponding author. E-mail: email@example.com
Abstract : Diabetes mellitus is a serious public health problem worldwide. Diabetic foot ulcers (DFU), a major complication in Type 2 diabetes are one of the major causes of morbidity and mortality around the world. To screen various bacterial pathogens present in diabetic foot ulcers and to determine their antibiotic sensitivity to actinomycetes isolated from various fields of Chandragiri, Tirupati, twenty four actinomycetes isolates were isolated and screened by primary and secondary screening methods to determine potent antibiotic producers by using test organisms. Among 24 isolates, 4 were more potent and they showed varied range of antibacterial activity of pathogens, isolated form diabetic foot ulcers. Four isolates were compared with lenezoid antibiotic. Enterococcus was resistant to lenezoid antibiotic but four actinomycetes inhibited the growth of Enterococi.
Keywords : Actinomycetes, Diabetic foot ulcers, Lenezoid, Antibacterial activity.