Applied and Natural Science Foundation
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Journal of Applied and Natural Science
An International Journal | Print ISSN: 0974-9411 | Online ISSN: 2231-5209
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Journal of Applied and Natural Science 2(2):190-193(2010)
Toxicity of Vernonia anthelmintica Linn. (Asteracea) seeds against mosquitoes vectors
M. F. Alam 1* , A.K. Chopra 2 , Mohammed M. Safhi 1 and V.K. Dua 3
1 Department of Pharmacology, Faculty of Pharmacy, JazanUniversity,Jazan, Kingdom of Saudi Arabia
2 Department of Zoology and Environmental Science, GurukulaKangriUniversity, Haridwar, India
3 National Institute of Malaria Research (ICMR) Field Station, BHEL, Haridwar, India
*Corresponding author. E-m ail:
Abstract : The Toxicological activity (larvicidal, adulticidal and repellent toxi City) of Vernonia anthelmintica seeds fraction was tested against different species of mosquito vectors viz, malaria (Anopheles culicifacies and Anopheles stephensi), filaria (Culex quinquefasciatus) and dengue (Aedes aegypti). The larvicidal toxi City of Vernonia anthelmintica seeds fraction was evaluated against the early 4 th instars larvae of different mosquitoes species. Mean LC50 value of the column fraction KAL-4 from seeds of V. anthelmintica against the larvae of An. culicifacies, An. stephensi, Culex quinquifaciatus and Aedes aegpyti were found to be 64 ppm, 70 ppm, 143 ppm and 166 ppm respectively. The larvicidal toxi City was more against An. culicifacies, An. stephensi than Culex quinquifaciatus and Aedes aegypti. The seed extracts did not show any adulticidal toxi City and repellent toxi City even at 10% concentrated impregnated paper and 5% on human hand, respectively.

Keywords : Toxicogical activity, Vernonia anthelmintica, Mosquitoes
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